Division of Infectious Diseases

#PharmToExamTable: Treatment of Clostridioides difficile infection in adults: Guideline review

This month’s #PharmToExamTable question was a review of Clostridioides difficile treatment guidelines:
-Answered by Andre Wilt, PharmD 2020 Graduate of UNMC College of Pharmacy (Reviewed by Scott Bergman PharmD and Andrew Watkins PharmD)

What is the optimal dosing of daptomycin for VRE bacteremia?

This month’s #PharmToExamTable question was answered by Xiaoxiao (Monica) Qi, PharmD 2020 UNMC graduate who is pursuing a PGY1 Pharmacy Residency at Avera McKennan Hospital and University Health Center in Sioux Falls, SD.It was reviewed by:Scott Bergman, PharmD, BCPS, BCIDP – Antimicrobial Stewardship Coordinator at Nebraska Medicine and Clinical Associate Professor at UNMC College of PharmacyAndrew Watkins, PharmD – PGY2 Infectious Diseases Pharmacy Resident at… Continue Reading

Antibiotics At the End-of-Life: Helping or Harming?

Content written by Dr. Clayton Mowrer. Early in my medical training, my father developed a rapidly-progressive type of cancer. Over the course of several months, his health declined quite quickly, and he was spending more time in the hospital than outside of it. It became uncomfortably clear that pushing forward with invasive and toxic interventions would cause him much more harm and discomfort than it… Continue Reading

#PharmToExamTable: What is the evidence for continuous infusion dosing of cefazolin?

The following is a clinical review written by Corey Paz, PharmD. Recent graduate of UNMC College of Pharmacy and new PGY1 Pharmacy Resident at Gunderson Health System in LaCrosse, Wisconsin. Follow him on Twitter @coreypaz. Corey was supervised by Scott Bergman, PharmD, FCCP, FIDSA, BCPS. Pharmacy Coordinator for Antimicrobial Stewardship at Nebraska Medicine and Clinical Associate Professor in the UNMC Dept of Pharmacy Practice and… Continue Reading

Introducing AMDA UTI Consensus Statement for Diagnosis, Treatment and Prevention of Urinary Tract Infections

The AMDA – The Society for Post-Acute and Long Term-Care Medicine convened a UTI consensus statement workgroup in 2017 to outline best practices for the management of UTI in post-acute and long-term care (PALTC) settings. The workgroup consisted of various national and international subject matter experts and was chaired by UNMC faculty Dr. Muhammad Salman Ashraf, who is an Associate Professor in the Division of Infectious Diseases…. Continue Reading

Antimicrobial Stewardship & Sepsis – A Great Debate

Optimal management of sepsis has long-been a holy grail in medicine. One area that remains fraught with debate is how to effectively balance the need for emergent antimicrobial administration with principles of antimicrobial stewardship. A recent Point–Counterpoint series on “Should Broad-Spectrum Antibiotics Be Routinely Administered to All Patients with Sepsis as Soon as Possible”published in CHEST highlights the debate. Disselkamp et al argue yes, early… Continue Reading

Unpacking the new IDSA Community-Acquired Pneumonia guidelines

We are always excited to have our ID fellows provide guest blog posts. Second year ID fellow Dr. Lindsey Rearigh (follow her on Twitter @LRearigh) was recently on her Antimicrobial Stewardship rotation and reviewed the latest published guidelines for Community-Acquired Pneumonia (CAP).  The American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA) recently released updated community-acquired pneumonia (CAP) guidelines. The first immediate implication… Continue Reading

Antimicrobial Resistance is a Global Problem: Notes from the World Health Summit

From the World Health Summit, Berlin: Panel on Antimicrobial Resistance (AMR), October 27, 2019. The 2019 World Health Summit (#WHS2019) opened with a panel discussion about the accelerating problem of global antimicrobial resistance (AMR). Dr. Peter Beyer, an intellectual property law expert working with the WHO on global health applications, led a panel of international experts to discuss current challenges of AMR – mostly focusing… Continue Reading

Nebraska Medicine receives IDSA Antimicrobial Stewardship Center of Excellence Designation

In 2018, the Infectious Diseases Society of America (IDSA) began recognizing “Antimicrobial Stewardship Centers of Excellence” at hospitals that meet or exceed best practice standards.  We are pleased to announce that Nebraska Medicine has recently been designated as an Antimicrobial Stewardship Center of Excellence effective October 2019.  As we celebrate #AntibioticAwarenessWeek for 2019, we are reminded of the importance of antimicrobial stewardship as antimicrobial resistance is… Continue Reading

Antimicrobial Stewardship efforts in the state of Nebraska

Content provided courtesy Dr. Salman Ashraf: Associate Medical Director, Nebraska Antimicrobial Stewardship Assessment and Promotion Program (ASAP) & Medical Director, Nebraska Infection Control Assessment and Promotion Program (ICAP) CDC’s most recent (2019) report on Antibiotic Resistance Threats in the United States describes 2.8 million infections due to antibiotic resistant organisms in the US resulting in over 35,000 deaths annually. The Division of Infectious Diseases at University… Continue Reading