By Alison Bobal
The Cochrane Library is a collection of six databases that contain different types of high-quality, independent evidence to inform healthcare decision-making. The Cochrane Library interface allows you to search across all of its databases.
The Cochrane Database of Systematic Reviews (updated monthly) is the leading resource for peer-reviewed systematic reviews in health care. It is valuable for finding information on the effectiveness of health care interventions and offers high-quality evidence on which to base clinical decisions.
The Cochrane Central Register of Controlled Trials is the largest database within the Cochrane Library and is a highly concentrated source of reports of randomized and quasi-randomized controlled trials. This database is updated monthly.
The Cochrane Methodology Register is a bibliography of publications that report on methods used in the conduct of controlled trials. It includes journal articles, books, and conference proceedings, and the content is sourced from MEDLINE and hand searches. This monthly updated database contains studies of methods used in reviews and more general methodological studies that could be relevant to anyone preparing systematic reviews.
The Health Technology Assessment Database brings together details of completed and ongoing health technology assessments (studies of the medical, social, ethical, and economic implications of healthcare interventions) from around the world and it updated monthly. The aim of the database is to improve the quality and cost-effectiveness of health care.
The NHS Economic Evaluation Database assists decision-makers by systematically identifying economic evaluations from around the world, appraising their quality, and highlighting their relative strengths and weaknesses. This database is not currently being updated.