Research Funding

Neuroprotection/Repair Therapeutics in MS

Deadline:  December 19, 2018

Through Fast Forward, the National Multiple Sclerosis Society has released a Request for Proposals to fund drug development opportunities for therapies promoting neuroprotection and repair relevant to multiple sclerosis.

  • Pre-Applications will be accepted starting October 24, 2018 
  • Final date for acceptance of pre-applications: December 5, 2018
  • Full Proposals will be due no later than December 19, 2018

Areas of high impact include:

* Therapeutic approaches that directly promote remyelination and/or neuroprotection — including stimulation of endogenous repair and cell-based approaches;

* Therapeutic approaches that directly modulate pathological innate immune responses;

* Proof-of-concept studies with repurposed FDA-approved therapies that have defensible intellectual property or strong commercial viability.

Appropriate proposals include, but are not limited to:

* Early-stage target validation;

* Optimization of pre-clinical compounds;

* PK/ADMET studies for valid compounds in development;

* Imaging studies to measure target occupancy or studies to measure target-related pharmacodynamic effects that could support a future clinical trial.

Research areas NOT supported by this RFP:

Assay development
Target identification studies
* High-throughput screening efforts


This RFP is open to commercial organizations and not-for-profit research institutions collaborating with a commercial organization. Consistent with our goal to support research and development conducted with a high level of quality control typical of the pharmaceutical industry, proposals from not-for-profit institutions will be considered if a majority of the work is conducted at reputable Contract Research Organizations with appropriate expertise relevant to the proposal.

Read more about this opportunity and how to apply.

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