Research Funding

IDeA Co-funding Initiative Announced

A request for nominations to the FY2018 IDeA Co-funding Initiative has been issued internally to NIH Institutes and Centers (ICs).

The IDeA Co-funding Initiative invites R01 and R15 submissions from NIH ICs.  The applications must be investigator-initiated and from institutions in IDeA-eligible states that were deemed meritorious in initial peer review, but are beyond the IC’s payline. The NIH ICs that have the primary assignment for the applications determine which of the applications they will nominate and send to NIGMS for consideration.

Investigators that are interested in their applications being considered for IDeA Co-funding should talk with the application’s Program Officer (PO) about their interest in this program. The deadline for nominations this year is COB April 6, 2018.

I serve as the NIGMS/IDeA point of contact for this initiative is and can be reached by phone (301-451-6416) or e-mail (rashada.alexander@nih.gov) with any questions about the program, so please contact me if you need more information. In addition, if your PO has questions about the program, please let them know that I am happy to answer their questions as well.

Best regards,

Rashada C. Alexander, Ph.D.
Program Director, Center for Research Capacity Building (CRCB)
National Institute for the General Medical Sciences (NIGMS)
National Institutes of Health (NIH)
45 Center Drive, 2AS43V
Bethesda, MD 20892-6200
(301) 451-6416
rashada.alexander@nih.gov 
Pronouns: she/her/hers

PCORI Funding for Pharmacological Treatment for Anxiety in Children, Adolescents, and/or Young Adults

LOI Deadline:  February 13, 2018
Town Hall Information Session:  January 31, 2018

Pharmacological Treatment for Anxiety in Children, Adolescents, and/or Young Adults – Cycle 1 2018

Notice of Upcoming PCORI Funding Announcement (PFA)

Research Initiative Highlights
The Patient-Centered Outcomes Research Institute (PCORI) seeks to fund high-quality clinical studies that compare the effectiveness of two or more pharmacological treatments for moderate to severe anxiety in children, adolescents, and/or young adults (e.g., comparisons of shorter-acting to longer-acting selective serotonin reuptake inhibitors (SSRIs) or comparisons of SSRIs to selective serotonin-norepinephrine reuptake inhibitors (SNRIs)) delivered in conjunction with cognitive behavioral therapy (CBT) or an alternative evidence-based psychological intervention.

For this PFA, PCORI is broadly interested in comparisons that are relevant and applicable to a spectrum of developmental stages represented by patients in the age range of 7 through 25 years. Applicants will be asked to clearly define the specific age range to be studied, and to provide a scientific rationale for the proposed study population.

Each proposed comparator must be clearly defined, evidence-based, and widely available, and applicants should ensure that all comparators are appropriate for the age range and disorder severity of the study population. Studies with a minimum follow-up period of one year from baseline are sought, with two years of follow-up preferred. In addition, all studies funded through this initiative must include robust sample sizes of at least 300 participants, with sufficient power demonstrated to conduct proposed analyses.

The maximum project budget is $15 million in direct costs, with a maximum project duration of five years.

This PFA preannouncement is provided to allow potential applicants additional time to identify collaborators, obtain stakeholder input on the research question, and develop responsive, high-quality proposals. Further details will be available in the full announcement to be released on January 16, 2018.

Challenge Prize to Expand Mobility for People with Lower-limb Paralysis

The Toyota Mobility Foundation and Nesta’s Challenge Prize Centre have just launched a technology challenge “to support radical improvements in the mobility and independence of individuals with lower-limb paralysis through the creation of smart personal assistive mobility devices that incorporate intelligent systems.”

Devices should use user-centered design and be capable of delivering measurable improvements in the everyday mobility and independence of a person with lower-limb paralysis. This could be accomplished through improved dynamic response to one or more of the following: user intention, surrounding environment, user’s body or the functional parameters of the device. The device should enable increased participation in the activities of daily living, work or leisure, while minimizing the cognitive load on the user; be comfortable and easy to use.

Small awards are available to develop prototypes needed to compete for the larger awards.

Read more about the Mobility Unlimited Challenge and Deadlines

A panel of expert judges will pick five finalists who will each receive $500,000 to take their concepts from an intelligent insight to a prototype. The Challenge winner will receive $1,000,000 to make the device available to users- with the winning concept unveiled in Tokyo in 2020.

The Mobility Unlimited Challenge aims to attract and support smaller innovators who might otherwise struggle to break into the assistive technology market. The Discovery Awards will provide seed funding of $50,000 for 10 groups with promising concepts, but who might otherwise lack the resources to enter the Challenge. Interested innovators can apply online at mobilityunlimited.org.

At the end of the Mobility Unlimited Challenge, the Toyota Mobility Foundation and Nesta’s Challenge Prize Centre will have supported teams of innovators in creating leading edge technological solutions, opening a new chapter in personal mobility for people with lower-limb paralysis.