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University of Nebraska Medical Center

National DNA Day 2025: Celebrating Genetics, One Base at a Time

national DNA Day April 25

by Morgan Blood and Lauren O’Leary, genetic counseling students

What is National DNA Day?

National DNA Day first began in 2003 and occurs annually on April 25. It is a day to recognize the discovery of DNA’s double helix in 1953 and the successful completion of the Human Genome Project in 2003. National DNA Day provides the opportunity to explore and celebrate the latest breakthroughs in genomic research and gain a deeper understanding of how these advancements can impact their lives.

What is DNA?

DNA, which stands for deoxyribonucleic acid, is made up of sugar, phosphate, and one of four nitrogen-containing bases: adenine (A), cytosine (C), guanine (G), and thymine (T). Discovered in 1953, DNA forms a double helix, or twisted ladder structure, with the rungs of this ladder made up of the four nitrogen-containing bases (A, C, G, and T). Our genes are made up of DNA which tells our bodies how to grow, develop, and function!

What is the Human Genome Project?

The Human Genome Project was a massive international collaboration aimed at sequencing – determining the specific organization of As, Cs, Ts, and Gs – the human genome for the first time. The project cost nearly three billion dollars. “Genome” is a fancy word that refers to the entire set of a person’s DNA. Each person’s genome is unique and plays a crucial role in keeping our bodies functioning each day.

In 1990, scientists began working to complete the Human Genome Project. After more than a decade, scientists successfully sequenced 92% of the human genome. The information gathered from the Human Genome Project helps researchers and healthcare providers identify underlying genetic explanations for patients and their symptoms.

Why does National DNA Day matter?

DNA Day is important because it provides an opportunity to learn about genetics, celebrate past accomplishments of genetics researchers, and inspire future studies to learn more about DNA. Genomics, or the study of the human genome, influences our everyday lives in so many different ways. Learn about how genomics influences our world.

Ways to get involved with National DNA Day:

The National Human Genome Research Institute (NHGI) provides several great resources to learn about genetics, including fun ways to celebrate DNA Day like creating DNA sequence friendship bracelets, filling in cell science coloring pages, and exploring a 3D Animation Database from The DNA Learning Center. Other ways to get involved include viewing educational videos, exploring the NHGI DNA Day website, and reaching out to the National DNA Day team with your questions. See below to access these resources to learn more!

Resources to learn more:

Explore the DNA Day website.

Contact the National DNA Day team with questions:

What is DNA? Watch on YouTube.

What is DNA and how does it work? Another YouTube video.

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