Research Funding

DOD Peer Reviewed Medical Research Program for Fiscal Year 2018

All applications for PRMRP funding must specifically address at least one of the Topic Areas as directed by Congress and must be directly relevant to the healthcare needs of military Service members, Veterans, and/or beneficiaries.  If the proposed research does not specifically address at least one of the FY18 PRMRP Topic Areas, the Government will administratively withdraw the application.  The Government reserves the right to reassign the application’s Topic Area if submitted under an inappropriate Topic Area.  The FY18 PRMRP Topic Areas are listed below.

  • Acute Lung Injury
  • Antimicrobial Resistance
  • Arthritis
  • Burn Pit Exposure
  • Cardiomyopathy
  • Cerebellar Ataxia
  • Chronic Migraine and Post-Traumatic Headache
  • Chronic Pain Management
  • Congenital Heart Disease
  • Constrictive Bronchiolitis
  • Diabetes
  • Dystonia
  • Eating Disorders
  • Emerging Infectious Diseases
  • Endometriosis
  • Epidermolysis Bullosa
  • Focal Segmental Glomerulosclerosis
  • Fragile X
  • Frontotemporal Degeneration
  • Guillain-Barré Syndrome
  • Hepatitis B and C
  • Hereditary Angioedema
  • Hydrocephalus
  • Immunomonitoring of Intestinal Transplants
  • Inflammatory Bowel Diseases
  • Interstitial Cystitis
  • Lung Injury
  • Malaria
  • Metals Toxicology
  • Mitochondrial Disease
  • Musculoskeletal Disorders
  • Myotonic Dystrophy
  • Non-Opioid Pain Management
  • Nutrition Optimization
  • Pancreatitis
  • Pathogen-Inactivated Blood Products
  • Post-Traumatic Osteoarthritis
  • Pressure Ulcers
  • Pulmonary Fibrosis
  • Respiratory Health
  • Rett Syndrome
  • Rheumatoid Arthritis
  • Scleroderma
  • Sleep Disorders
  • Spinal Muscular Atrophy
  • Sustained-Release Drug Delivery
  • Tinnitus
  • Tissue Regeneration
  • Tuberculosis
  • Vaccine Development for Infectious Diseases
  • Vascular Malformations
  • Women’s Heart Disease

The mission of the PRMRP is to encourage, identify, and select military health-related research of exceptional scientific merit. Relevance to the healthcare needs of military Service members, Veterans, and their family members is a key feature of each FY18 PRMRP award mechanism.

http://cdmrp.army.mil/funding/prmrp

Discovery Award – Letter of Intent due June 14, 2018

  • Postdoctoral fellow or clinical fellow (or equivalent) and above.
  • Supports the exploration of a highly innovative new concept or untested theory in the Topic Area(s) of interest.
  • Not intended to support the logical progression of an already established line of questioning.
  • Clinical trials will not be funded.
  • Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborator(s), and their organization(s).
  • Maximum of $200,000 for direct costs (plus indirect costs)
  • Maximum period of performance is 18 months

 

Focused Program Award – Preproposal due June 19, 2018

  • Lead PI: Full Professor level or above (or equivalent)
  • Project leads: Assistant Professor level or above (or equivalent)
  • Preproposal submission is required; application submission is by invitation only.
  • Supports a synergistic, multidisciplinary research program of at least four distinct but complementary projects addressing an overarching goal in the Topic Area(s) of interest.
  • Projects should work together to answer critical questions, resolve differing hypotheses, and translate laboratory findings to clinical applications.
  • Projects may range from exploratory/hypothesis-developing through small-scale clinical trials that together will address the overarching goal/question.
  • Research team of highly qualified, multidisciplinary project leaders should be led by a PI with demonstrated success in directing large, focused projects.
  • Maximum of $10 million for total costs (includes direct and indirect costs)
  • Maximum period of performance is 4 years

 

Investigator-Initiated Research Award – Preproposal due June 12, 2018

  • Assistant Professor level or above (or equivalent)
  • Preproposal submission is required; application submission is by invitation only.
  • Supports research that will make an original and important contribution to the field of research or patient care in the topic area(s) of interest.
  • Partnering PI Option available.
  • Clinical trials will not be funded.
  • Maximum of $1.2 million for direct costs (plus indirect costs)
  • Maximum of $1.5 million for direct costs (plus indirect costs) for applications including a Partnering PI Option
  • Maximum period of performance is 3 years

 

Technology/ Therapeutic Development Award – Preproposal due June 12, 2018

 

      • Assistant Professor level or above (or equivalent)
      • Supports the translation of promising preclinical findings into clinical applications for prevention, detection, diagnosis, treatment, or quality of life in the Topic Area(s) of interest.
      • Product-oriented (e.g., device, drug, clinical guidelines). The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product.
      • Clinical trials will not be funded.
      • Preproposal submission is required; application submission is by invitation only.
      • Maximum of $3.0 million for direct costs (plus indirect costs)
      • Maximum period of performance is 3 years

    A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions that are available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

    Applications must be submitted through the federal government’s single-entry portal, Grants.gov. For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the PRMRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).

    Point of Contact:

    CDMRP Help Desk
    301-682-5507
    help@eBrap.org

2017 AIMM Call for Proposals Released

LOI Deadline: January 26, 2018
Award:  $350,000

The AIMM Research Award is intended to support highly creative and conceptually innovative high-risk research with the potential to accelerate critical discoveries or major advancements that will significantly impact military health and medicine. AIMM initiative funding supports novel research concepts and other efforts that initiate or enhance potential game-changers that may not be supported by other funding mechanisms or core programs. Applications using synthetic or systems biology-based approaches are highly encouraged.

The anticipated direct costs budgeted for the entire period of performance for an FY17 AIMM Research Award will not exceed $350,000. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.

Funding for this award mechanism supports applied research. Applied research utilizes systematic studies to understand the means to meet a recognized and specific need. It is a systematic expansion and application of knowledge to develop useful materials, devices, and systems or methods. It may be oriented, ultimately, toward the design, development, and improvement of prototypes and new processes to meet general mission area requirements.  Applied research may translate promising basic research into solutions for broadly defined military needs, short of system development. Applied research may include hypothesis-testing and/or proof-of-concept studies as well as work that refines concepts and ideas into potential solutions with a view toward evaluating technical feasibility of emerging approaches, technologies, and promising new products.

Proposed research may involve human subjects, but clinical trials do not meet the intent of this award mechanism. A clinical trial is defined as a prospective accrual of patients (human subjects) in whom an intervention (e.g., device, drug, biologic, surgical procedure, rehabilitative modality, behavioral intervention, or other) is tested for a measurable outcome with respect to safety, effectiveness, and/or efficacy. This outcome represents a direct effect on the subject of that intervention or interaction.

Important aspects of the AIMM initiative are as follows:
• Impact: The proposed research is expected to make an important and original contribution to advancing solutions relevant to military health and medicine and
ultimately lead to improved outcomes for Service members, Veterans, or military beneficiaries.
• Innovation: Research deemed innovative may represent a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities. Research may be innovative in study concept, research methods or technology, or adaptations of existing methods or technologies. Research that represents an incremental advance on previously published work is not considered innovative.

Download the RFA

DoD Spinal Core Injury Research Program

FY17 SCIRP Program Announcements and General Application Instructions for the following award mechanisms are posted on Grants.gov.

As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency (DHA), J9 Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation.  The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).

 

Clinical Research Development Award – Preproposal due August 8, 2017

Independent investigators at all academic levels (or equivalent)

  • Preproposal is required; application submission is by invitation only.
  • Fund research that will establish the necessary collaborations and develop the necessary research resources that will serve as a foundation for investigator-initiated clinical research.
  • Clinical trials not allowed.
  • Maximum funding of $100,000 for direct costs (plus indirect costs)
  • Maximum period of performance is year

 

Clinical Trial Award – Preproposal due August 8, 2017

Independent investigators at all academic levels (or equivalent)

  • Preproposal is required; application submission is by invitation only.
  • Fund Phase 0, I, or II clinical trials with the potential to have a major impact on treatment or management of spinal cord injury (SCI) and its consequences.
  • Preclinical data required for all clinical trial applications.
  • Maximum funding of $2,000,000 for direct costs (plus indirect costs)
  • Maximum period of performance is years

 

Investigator-Initiated Research Award – Preproposal due August 8, 2017

Independent investigators at all academic levels (or equivalent)

  • Preproposal is required; application submission is by invitation only.
  • Fund SCI-related research that has the potential to make an important contribution to SCI research and/or patient care.
  • Preliminary data required.
  • Clinical trials not allowed.
  • Maximum funding of $500,000 for direct costs (plus indirect costs)
  • Maximum period of performance is 3 years

 

Qualitative Research Award – Preapplication due August 8, 2017

Independent investigators at all academic levels (or equivalent)

  • Preproposal is required; application submission is by invitation only.
  • Fund qualitative research on military Service members and Veterans in the years following SCI.
  • Qualitative research is defined as a form of social inquiry that focuses on understanding the way that people interpret and make sense of their experiences and the world in which they live (i.e., seek to understand the human experience).
  • Preliminary data encouraged, but not required.
  • Clinical trials not allowed.
  • Maximum funding of $500,000 for direct costs (plus indirect costs)
  • Maximum period of performance is years

Translational Research Award – Preproposal due August 8, 2017

Independent investigators at all academic levels (or equivalent)

  • Preproposal is required; application submission is by invitation only.
  • Fund studies that accelerate the movement of promising ideas in SCI research into clinical applications.
  • Optional Feature:  Applications that include a Qualified Collaborator that meets criteria identified in the announcement may apply for a higher level of funding.
  • Preliminary data required.
  • Limited clinical testing of a novel intervention or device is permissible.
  • Maximum funding of $1,250,000 for direct costs (plus indirect costs)
  • Maximum funding of $1,500,000 for direct costs (plus indirect costs) for applications including an Optional Qualified Collaborator
  • Maximum period of performance is years

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions available for electronic downloading from the Grants.gov website.  The application package containing the required forms for each award mechanism will also be found on Grants.gov.  A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

 

Applications must be submitted through the Federal Government’s single-entry portal, Grants.gov.  For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org.  For more information about the SCIRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).

Point of Contact:

CDMRP Help Desk
301-682-5507
help@eBrap.org