La Jolla Institute for Allergy & Immunology
This postdoc will be responsible for performing and analyzing single-cell and bulk RNA-Seq assays on a large, multi-center project characterizing the memory T cell immune signatures associated with Mycobacterium tuberculosis and dengue virus infection. These analyses will define the transcriptomic profiles of CD4+ and CD8+ T cells in individuals previously exposed to either pathogen, currently experiencing active disease, or who have been vaccinated; the overall goal is to determine whether certain immune signatures are associated with preferential expansion or contraction of certain pre-existing subsets of T cells. This is a large-scale study employing samples from numerous sites around the globe, allowing conclusions regarding the extent of generalizability.
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Desired skills and experience
The ideal postdoctoral candidate will have experience in molecular biology and immunology,. The candidate should also be comfortable working in a large, interdisciplinary research group, as this project will involve extensive interaction with immunologists, clinical coordinators, and bioinformaticians.
Interested individuals must include their curriculum vitae and the names of three references.
About the employer
Our independent, non-profit research institute is currently seeking a highly motivated researcher for an immediate opening in the research group of Dr. Alessandro Sette.
Successful candidates will join an interdisciplinary group of researchers dedicated to the identification and characterization of protective T cell epitopes from a variety of complex antigens, such as allergens, viruses, and bacteria.