{"id":196,"date":"2017-05-12T08:00:56","date_gmt":"2017-05-12T13:00:56","guid":{"rendered":"https:\/\/blog.unmc.edu\/infectious-disease\/?p=196"},"modified":"2017-05-05T11:05:08","modified_gmt":"2017-05-05T16:05:08","slug":"id-journal-club-on-hpv-vaccination","status":"publish","type":"post","link":"https:\/\/blog.unmc.edu\/infectious-disease\/2017\/05\/12\/id-journal-club-on-hpv-vaccination\/","title":{"rendered":"ID Journal Club on HPV Vaccination"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p><strong>What Are You Reading?<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-197\" src=\"https:\/\/blog.unmc.edu\/infectious-disease\/wp-content\/uploads\/sites\/54\/2017\/05\/Capture-300x128.jpg\" alt=\"\" width=\"391\" height=\"167\" srcset=\"https:\/\/blog.unmc.edu\/infectious-disease\/wp-content\/uploads\/sites\/54\/2017\/05\/Capture-300x128.jpg 300w, https:\/\/blog.unmc.edu\/infectious-disease\/wp-content\/uploads\/sites\/54\/2017\/05\/Capture-120x51.jpg 120w, https:\/\/blog.unmc.edu\/infectious-disease\/wp-content\/uploads\/sites\/54\/2017\/05\/Capture.jpg 575w\" sizes=\"auto, (max-width: 391px) 100vw, 391px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-family: 'Calibri',sans-serif;color: black\">At the last Infectious Diseases Journal Club,\u00a0I reviewed &#8220;Quadrivalent HPV Vaccination and the Risk of Adverse Pregnancy Outcomes&#8221;, a comprehensive review published in the <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1612296\">March 30th, 2017 issue of The New England Journal of Medicine <\/a>that\u00a0examined adverse pregnancy outcomes between women who received the quadrivalent\u00a0HPV vaccine during pregnancy and those who did not. \u00a0I trained in both internal medicine and pediatrics and\u00a0studies like this one pique my interest as the implications span across the\u00a0fields. \u00a0The HPV vaccine is recommended for all women ages 9-26 years, but few data exist regarding the vaccine during pregnancy. \u00a0The\u00a0study&#8217;s\u00a0data showed that the children born to\u00a0women vaccinated with the quadrivalent HPV vaccine during pregnancy\u00a0did not have a significantly higher rate of major birth defects compared to children born to women who were not vaccinated with the quadrivalent HPV vaccine during pregnancy. \u00a0Also, the number of spontaneous abortions, preterm births, infants with low birth weight, infants who were small for gestational age, and stillbirths were not higher in the vaccinated cohorts than in the unvaccinated cohorts. \u00a0This data therefore supports the safety of HPV vaccines if they are inadvertently given in pregnancy. \u00a0For me, this study highlights the need for vaccine\u00a0studies to include pregnant women who until recently were classified as\u00a0a &#8220;vulnerable population&#8221; by the Common Rule, the\u00a0ethical framework that guides biomedical research in humans in the United States.<\/span><\/p>\n<p><em>&#8211; Content courtesy of Dr. Andrea Green<\/em><\/p>\n<form name=\"s2form\" method=\"post\" action=\"https:\/\/blog.unmc.edu\/infectious-disease\/subscribe2\/\"><input type=\"hidden\" name=\"ip\" value=\"216.73.216.21\" \/><span style=\"display:none !important\"><label for=\"firstname\">Leave This Blank:<\/label><input type=\"text\" id=\"firstname\" name=\"firstname\" \/><label for=\"lastname\">Leave This Blank Too:<\/label><input type=\"text\" id=\"lastname\" name=\"lastname\" \/><label for=\"uri\">Do Not Change This:<\/label><input type=\"text\" id=\"uri\" name=\"uri\" value=\"http:\/\/\" \/><\/span><p><label for=\"s2email\">Your email:<\/label><br><input type=\"email\" name=\"email\" id=\"s2email\" value=\"Enter email address...\" size=\"20\" onfocus=\"if (this.value === 'Enter email address...') {this.value = '';}\" onblur=\"if (this.value === '') {this.value = 'Enter email address...';}\" \/><\/p><p><input type=\"submit\" name=\"subscribe\" value=\"Subscribe\" \/>&nbsp;<input type=\"submit\" name=\"unsubscribe\" value=\"Unsubscribe\" \/><\/p><\/form>\r\n\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>What Are You Reading? &nbsp; &nbsp; At the last Infectious Diseases Journal Club,\u00a0I reviewed &#8220;Quadrivalent HPV Vaccination and the Risk of Adverse Pregnancy Outcomes&#8221;, a comprehensive review published in the March 30th, 2017 issue of The New England Journal of Medicine that\u00a0examined adverse pregnancy outcomes between women who received the quadrivalent\u00a0HPV vaccine during pregnancy and [&hellip;]<\/p>\n","protected":false},"author":532,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_s2mail":"yes","footnotes":""},"categories":[1],"tags":[10,3],"class_list":["post-196","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-readid","tag-unmcid"],"_links":{"self":[{"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/posts\/196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/users\/532"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/comments?post=196"}],"version-history":[{"count":2,"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/posts\/196\/revisions"}],"predecessor-version":[{"id":212,"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/posts\/196\/revisions\/212"}],"wp:attachment":[{"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/media?parent=196"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/categories?post=196"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.unmc.edu\/infectious-disease\/wp-json\/wp\/v2\/tags?post=196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}